computer agents,
native on your mac.

Your command center for AI agents that work while you sleep. Synced across Mac, iPhone, iPad, and the web.

Download for macOS

PioneerAI

FireChatbot

DocGPT

The best way to work with agents.

Built to work while you sleep.

Schedule a research report for Monday at 6 AM. Deploy an agent that monitors competitors weekly. Your agents run in the cloud 24/7 — they don't need your laptop open, and they don't need you watching. Wake up to results.

Your agents remember everything.

Persistent workspaces. Every conversation, every file, every decision — carried across sessions. Your agent learns your codebase, your writing style, your preferences. Day 1, you explain your project. Day 30, it works without asking.

Skills that go beyond chat.

Web search, image generation, deep research, and custom MCP servers. Your agents don't just answer questions — they browse the web, generate assets, conduct multi-step research, and connect to the tools you already use.

run a deep research operation to find papers with brillant ideas about possible completely new ways to treat cancer, that are not yet widely recognized, because the authors are not famous enough. Use the image generation tool to create some very good visualizations when crafting the report about the treatment idea you found and include them there.

1/20/2026 at 18:47:52

Default Agent

Default

Using Deep Research Skill46s

Underrated Cancer Treatment Innovations

Key Focus Area: Physics-based therapies appear to be an underexplored frontier. I'm finding promising work on mechanical destruction of cancer cells using ultrasound resonance (Oncotripsy) and molecular-scale vibrations triggered by near-infrared light.

Emerging Paradigm: Non-canonical cell death mechanisms offer novel therapeutic targets. Methuosis, alkaliptosis, and oxeiptosis represent pathways that cancer cells haven't evolved resistance to, unlike traditional apoptosis-inducing treatments.

Bioelectric Research: Michael Levin's work at Tufts University on bioelectricity and cancer reversion is particularly compelling. The idea that cancer might be a reversible disorder of cellular communication patterns rather than purely genetic mutations opens entirely new treatment possibilities.

Sources (5)

pubmed.ncbi.nlm.nih.gov nature.com sciencedirect.com arxiv.org biorxiv.org

/workspace/research/underrated-cancer-treatments.md

File is empty or no content returned

Excellent! Now I'll create compelling visualizations to enhance this comprehensive report. I'll generate:

A title image for the report header
A visualization for Oncotripsy (ultrasound resonance)
A visualization for Molecular Jackhammers
A visualization showing the different non-canonical cell death mechanisms

Using Image Generation Skill9m 9s

Perfect! Now I'll insert these visualizations into the report at strategic locations.

File modified successfully

📃

underrated-cancer-treatments.md

Deep Research Complete: Underrated Cancer Treatment Innovations

I've successfully completed a comprehensive deep research operation and created a fully illustrated report on under-recognized, innovative cancer treatment approaches.

Report Location

/workspace/research/underrated-cancer-treatments.md

Key Findings - Breakthrough Concepts Discovered

The research identified 6 major under-recognized treatment paradigms:

1. Physics-Based Therapies

Oncotripsy: Using tuned ultrasound resonance to mechanically shatter cancer cells

Molecular Jackhammers: Near-infrared light causes molecules to vibrate, physically tearing apart cancer cell membranes

2. Non-Canonical Cell Death

Methuosis: Cancer cells "drink themselves to death" through excessive fluid intake

Alkaliptosis: pH-dependent death triggered by intracellular alkalinization

Oxeiptosis: Novel ROS-induced death pathway

3. Cancer Reversion via Bioelectricity

Michael Levin's work showing cancer as a reversible disorder of bioelectric signaling
Ion channel modulation to "reprogram" malignant cells back to normal

4. Deuterium Depletion

Altering isotopic water content to disrupt cancer cell metabolism

Visualizations Created

I generated 5 high-quality scientific illustrations and integrated them into the report with captions.

The full 34,000+ character report includes detailed mechanisms, key researchers, and a comprehensive citation list with 51 sources.

152 Compute Tokens

Your desktop. Your Agent's Cloud Computer.

Each of your agents gets its own isolated cloud environment with persistent storage, custom runtimes, installed tools, running 24/7. The Mac app puts you in control. Monitor progress in real time, review results, and drag files straight from Finder into any workspace. Start a task on your Mac. Check the results from your phone.

Native Mac Experience

Built for macOS. Keyboard shortcuts, menu bar, native notifications, sidebar, toolbar, and drag & drop — the way a Mac app should feel.

Seamless Across Every Device

Start a task on your Mac, check progress from your iPhone, review results on your iPad, or manage everything from the web. Agents, files, and conversations stay in sync.

Drag, Drop, Share

Drop files from Finder into Computer Agents. They're instantly available to all your agents and accessible from any device. No upload dialogs. No friction.

Cloud Runtime Environments

Define exactly what your agent needs — Python, Node.js, system packages, environment variables, encrypted secrets. Each environment is an isolated cloud computer, configured to your spec.

Full API Access

Everything you do in the app, you can do through the API. Create threads, manage environments, stream responses, and integrate agents directly into your own products.

Skills & Integrations

Web search, image generation, deep research, GitHub, Notion, Google Drive, and custom MCP servers. Extend what your agents can do — without writing a line of code.

System Requirements

macOS Sequoia 15.0 or later

Apple Silicon or Intel Mac

Internet connection required

Put AI to work.

Download Computer Agents for Mac. Give your agents a cloud computer, schedule tasks, and access everything from any device.

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computer agents,native on your mac.